Neonatal Sepsis Risk

Name: Neonatal Sepsis Risk
Creator: Daniel Diaz-Gil, MD
Keywords: sepsis, EOS, early-onset, neonatal, newborn, GBS, chorioamnionitis, PROM, antibiotics, risk assessment, AAP, 2018, group B strep, intrapartum

Early-onset neonatal sepsis risk stratification per AAP 2018 algorithm

Clinically Verified· 5 tests

For educational and informational purposes only. Verify all results before clinical application.

Gestational Age *

weeks

Gestational age in completed weeks (34-42 weeks)

Clinical Appearance *

GBS Status *

GBS Prophylaxis *

Adequate = penicillin or ampicillin given ≥4 hours before delivery

Duration of Rupture of Membranes *

hours

Maternal Temperature *

°C

Chorioamnionitis *

References

Puopolo KM, Benitz WE, Zaoutis TE, et al. Management of Neonates Born at ≥35 0/7 Weeks of Gestation With Suspected or Proven Early-Onset Bacterial Sepsis. Pediatrics. 2018;142(6):e20182894.[DOI]
Verani JR, McGee L, Schrag SJ. Prevention of Perinatal Group B Streptococcal Disease: Revised Guidelines from CDC, 2010. MMWR Recomm Rep. 2010;59(RR-10):1-36.
Escobar GJ, Puopolo KM, Wi S, et al. Stratification of Risk of Early-Onset Sepsis in Newborns ≥34 Weeks Gestation. Pediatrics. 2014;133(1):30-36.[DOI]

Reviewed by Daniel Diaz-Gil, MD · Last updated March 2026

Medical disclaimer

This tool is for educational and informational purposes only. It is not a substitute for professional clinical judgment. Always independently verify results before making clinical decisions.

Professional Resources — Tools used by pediatricians for clinical scoring

PEWS Reference CardsPediatric Early Warning Score quick-reference cards for bedside use~$15via Amazon Pediatric Digital ScaleAccurate weight measurement for clinical assessment~$40via Amazon BoardVitals Pediatrics QbankBoard-style questions for general pediatrics certificationsubscriptionvia BoardVitals