Anion Gap

Name: Anion Gap
Creator: Daniel Diaz-Gil, MD
Keywords: anion gap, metabolic acidosis, HAGMA, NAGMA, delta-delta, delta ratio, albumin corrected, acidosis, DKA, lactic acidosis, toxicology

Calculates anion gap with albumin correction and delta-delta ratio for metabolic acidosis evaluation

Clinically Verified· 5 tests

Source: Emmett M, Narins RG. Clinical use of the anion gap. Medicine (Baltimore). 1977;56(1):38-54.

For educational and informational purposes only. Verify all results before clinical application.

Sodium (Na) *

mEq/L

Chloride (Cl) *

mEq/L

Bicarbonate (HCO3) *

mEq/L

Albumin

g/dL

Default 4.0 g/dL; adjust for hypoalbuminemia correction

References

Emmett M, Narins RG. Clinical use of the anion gap. Medicine (Baltimore). 1977;56(1):38-54.[DOI]
Figge J, Jabor A, Kazda A, Fencl V. Anion gap and hypoalbuminemia. Crit Care Med. 1998;26(11):1807-1810.[DOI]

Reviewed by Daniel Diaz-Gil, MD · Last updated March 2026

Medical disclaimer

This tool is for educational and informational purposes only. It is not a substitute for professional clinical judgment. Always independently verify results before making clinical decisions.

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