Febrile Infant Inflammatory Markers

Name: Febrile Infant Inflammatory Markers
Creator: Daniel Diaz-Gil, MD
Keywords: febrile infant, fever, neonate, inflammatory markers, CRP, procalcitonin, ANC, urinalysis, AAP 2021, sepsis, meningitis, UTI, infant fever workup

AAP 2021 inflammatory marker assessment for well-appearing febrile infants 8–60 days old

Clinically Verified· 5 tests

For educational and informational purposes only. Verify all results before clinical application.

Age (days) *

days

Age in days (8–60) for well-appearing febrile infant

Absolute Neutrophil Count (ANC) *

cells/µL

ANC ≥4,090 cells/µL is considered positive

C-Reactive Protein (CRP) *

mg/L

CRP ≥20 mg/L is considered positive

Procalcitonin *

ng/mL

Procalcitonin ≥0.5 ng/mL is considered positive

Urinalysis Result *

References

Pantell RH, Roberts KB, Adams WG, et al. Evaluation and Management of Well-Appearing Febrile Infants 8 to 60 Days Old. Pediatrics. 2021;148(2):e2021052228.[DOI]

Reviewed by Daniel Diaz-Gil, MD · Last updated March 2026

Medical disclaimer

This tool is for educational and informational purposes only. It is not a substitute for professional clinical judgment. Always independently verify results before making clinical decisions.

Professional Resources — Tools used by pediatricians for infectious disease management

Red Book: Report of the Committee on Infectious Diseases (AAP)AAP guidelines for pediatric infectious disease~$110via Amazon Vancomycin Dosing Reference CardQuick-reference for pediatric vancomycin dosing and monitoring~$10via Amazon

Also used with

Neonatal Sepsis Risk Clinical Scores UTICalc Clinical Scores Bacterial Meningitis Score Infectious Disease